Rendering all sprites to a texture or as separate quads?

Rendering all sprites to a texture or as separate quads?

I'm wondering what the most effective way to render sprites using Stage3D
is? Do I render them into one texture (kind of like rendering everything
into a BitmapData buffer), or do I render them into separate textured
quads (Using starling, for example)?
I will probably end up with quite a lot of sprites, since I plan on
writing a tile map engine, that can probably have layered tile maps etc.
Best Regards, Tomas